Setting Up An Email Auto-Responder (or Vacation Message) In cPanel

Point your browser to www.yourdomain.com/cpanel.
If any security certificate alerts pop up, you can safely accept these. Our servers use a self-generated security certificate which keeps the data from the control panel secure when you visit it.
Login to the control panel using your username and password supplied to you at sign up.
Click the 'Mail' option, which is the very first icon.
Next click the 'Auto Responders' link toward the bottom of the page.
Click the 'Add Auto Responder' link.
Fill in the email account name for which you need the responder set up.
Insert your name into the "From" input box.
You can leave the subject as 'Re: %subject%' (which will insert the subject they used when sending you the email) or change to one of your own.
Only change the character set if you know what you are using!
If you want the email sent as an HTML email, you can check the box.
Now fill in your response message in the 'Body' text box. You shouldn't make it too long, since every email sent to the address you chose will get this in reply.
When you've filled in all the parts to the form, submit it by clicking 'Create/Modify'.
Did you notice the 'modify' there on the button? Yes, you can come back and change this should the need arise. Follow the steps to the Auto-Responders admin page and you'll see a list of those already set up. Click 'Edit' next to the one to change.
When you no longer need the auto-responder you can simply remove it from the list by clicking 'Delete'.
Note: an auto-responder that is set up without a corresponding email account or forwarder will simply erase the email once it replies to it. To be sure you keep those emails, create either a real email account or an email forwarder.